Behavioural Neurology

Behavioural Neurology / 2006 / Article
Special Issue

TMS Improvement of Human Cogntitive Abilities

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Volume 17 |Article ID 793256 |

Simone Rossi, Stefano F. Cappa, Monica Ulivelli, Alberto De Capua, Sabina Bartalini, Paolo M. Rossini, "rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?", Behavioural Neurology, vol. 17, Article ID 793256, 5 pages, 2006.

rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?

Received21 Nov 2006
Accepted21 Nov 2006


Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms.

Copyright © 2006 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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