Behavioural Neurology

Behavioural Neurology / 2012 / Article

Open Access

Volume 25 |Article ID 501979 | 8 pages | https://doi.org/10.3233/BEN-2012-110236

Post-Stroke Depression: Main Phenomenological Clusters and their Relationships with Clinical Measures

Received17 Feb 2012
Accepted17 Feb 2012

Abstract

Objectives: To investigate the principal psychopathological dimensions of post-stroke depression (PSD) through the assessment of the factorial structure of the Post-Stroke Depression Rating Scale (PSDRS).Methods: We enrolled ninety-eight subjects with PSD, who underwent the PSDRS, MMSE and Barthel Index. Information about demographic, clinical, and neuroanatomical factors was collected.Results: The factor analysis extracted three factors accounting for 63.4% of the total variance, and identified as: (1) “Depressive and Anxious Symptoms“ (DAS); (2) “Lack of Emotional Control” (LEC); 3) “Reduced Motivation” (RM). On multivariate statistics, DAS severity was predicted by previous history of mood disorders and Barthel Index; LEC severity was predicted by Barthel Index; RM severity was predicted by age.Conclusions: The PSDRS displayed a reliable factor structure that agreed with previous interpretation of PSD. In particular, core depressive symptoms seem to be related to premorbid personality and functional status, whereas apathy/anhedonia may be connected to brain aging.

Copyright © 2012 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


More related articles

563 Views | 750 Downloads | 6 Citations
 PDF  Download Citation  Citation
 Order printed copiesOrder

Related articles

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.