Table of Contents Author Guidelines Submit a Manuscript
Behavioural Neurology
Volume 27, Issue 1, Pages 47-55

Functional Neuroimaging Investigations of Motor Networks in Tourette Syndrome

Aribert Rothenberger1 and Veit Roessner2

1Child and Adolescent Psychiatry, Universitymedicine Göttingen, Göttingen, Germany
2Child and Adolescent Psychiatry, Technical University Dresden, Dresden, Germany

Received 23 November 2012; Accepted 23 November 2012

Copyright © 2013 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Motor and vocal tics are the core symptom of Tourette syndrome (TS). Tic generation seems to develop throughout the known motor pathways. This review focuses on functional neuroimaging in order to check this assumption. Also it elucidates the alterations and interactions of motor networks in TS depending on different contexts and circumstances like resting state, spontaneous tic movements, suppression of tics and premonitory urges, voluntary goal-oriented movements as well as electrophysiological neuronal stimulation. In general, the primary tic generating motor network uses the basic motor pathways differently, interacts with secondary sensorimotor networks and neuronal systems of cognitive behavioural control in a merely hierarchical manner, changing during neurodevelopment.