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Behavioural Neurology
Volume 26 (2013), Issue 3, Pages 207-209

Functional Brain Activity within the Medial and Lateral Portion of BA10 during a Prospective Memory Task

Francesco Barban,1,2 Giovanni Augusto Carlesimo,1,3 Emiliano Macaluso,2 Carlo Caltagirone,1,3 and Alberto Costa1

1Clinical and Behavioural Neurology Laboratory, IRCCS Fondazione Santa Lucia, Rome, Italy
2Neuroimaging Laboratory, IRCCS Fondazione Santa Lucia, Rome, Italy
3Institute of Neurology, University of Rome “Tor Vergata”, Rome, Italy

Received 21 May 2012; Accepted 21 May 2012

Copyright © 2013 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In this study we tested the gateway hypothesis of Broadmann area 10 (BA10). With a functional magnetic resonance imaging (fMRI) protocol we manipulated the saliency–stimulus-oriented (SO) attending– and the memory load – stimulus-independent (SI) attending–during a prospective memory (PM) task. We found a significant main effect of the SO manipulation within the medial BA10 and a significant interaction between SI attending and PM task within the left lateral BA10. Our results give experimental support to the gateway hypothesis.