Behavioural Neurology

Behavioural Neurology / 2013 / Article
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Includes Special Section: Abstracts from the Joint Meeting of the FESN/GNP, Sept. 12-14, 2013, Berlin, Germany

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Clinical Note | Open Access

Volume 27 |Article ID 547853 | https://doi.org/10.3233/BEN-120257

Colin Singam, Mark Walterfang, Ramon Mocellin, Andrew Evans, Dennis Velakoulis, "Topiramate for Abnormal Eating Behaviour in Frontotemporal Dementia", Behavioural Neurology, vol. 27, Article ID 547853, 2 pages, 2013. https://doi.org/10.3233/BEN-120257

Topiramate for Abnormal Eating Behaviour in Frontotemporal Dementia

Received29 Mar 2013
Accepted29 Mar 2013

Abstract

Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. This report describes a man with frontotemporal dementia, behavioural variant, associated with abnormal eating behaviour which appeared to respond to topiramate. We review the physiological basis of abnormal eating behaviour in frontotemporal dementia and explore possible mechanisms of action by which topiramate may modify eating behaviour in this condition.

Copyright © 2013 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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