A patient with primary CNS lymphoma involving the left-sided thalamus, the internal capsule, and the anterior part of the corpus callosum seen as hypointensity on axial unenhanced T1-weighted imaging (a), hyperintensity on coronal T2-weighted (b) and axial FLAIR (c) imaging, with multifocal enhancement on axial (d) and coronal (e) gadolinium-enhanced T1-weighted imaging.