Mapping Remote Subcortical Ramifications of Injury after Ischemic Strokes
Figure 1
(a) Image processing steps utilized to quantify hemisphere connectivity. A white matter link was considered significantly reduced if the number of fibers connecting a pair of Brodmann areas in the left hemisphere (with stroke) was less than 2.5% of the number connecting the pair of homologous Brodmann areas in the right hemisphere. Fibers located within the necrotic lesion were excluded from this analysis. (b) The original necrotic lesion site (dark gray) and the significantly reduced white matter pathways (orange) relative to the right hemisphere are demonstrated in three-dimensional reconstructions and representative slices for each patient. The images are skull stripped for better visualization of the location of the necrotic tissue.
