Pain in Parkinson's Disease Associated with COMT Gene Polymorphisms

Table 3

COMT genotype and PD related pain.

	PD-related pain; (𝑁=35)	Non-PD-related pain (𝑁=20)	AD; OR (95% CI)	𝑃 value (AD)	AR; OR (95% CI)	𝑃 value; (AR)
rs4633
CC	14 (0.400)	11 (0.550)	0.458 (0.120–1.751)	0.254
CT	19 (0.543)	8 (0.400)
TT	2 (0.057)	1 (0.050)			1.156 (0.070–19.105)	0.919
rs6267
GG	22 (0.629)	11 (0.550)	1.384 (0.346–5.526)	0.646
GT	13 (0.371)	7 (0.350)
TT	0 (0)	2 (0.100)			4.509𝐸9 (0.000)	0.999

Binary logistic regression was used; covariates were age, sex, onset age, duration of disease, duration of L-Dopa medication, and UPDRS. FDR correction was not performed for 𝑃>0.05.