Pain in Parkinson's Disease Associated with COMT Gene Polymorphisms

Table 4

Clinical factors on pain in PD patients.

	PD with pain (𝑁=55)	PD without pain (𝑁=42)	𝐹 value	𝑃
Age (years)	65.44±9.88	66.43±10.27	0.232	0.631
Onset age (years)	59.58±9.85	61.57±10.75	0.897	0.346
Duration of PD (years)	5.85±2.99	4.86±3.18	2.506	0.117
Duration of medication (years)	3.47±2.02	2.92±2.24	1.647	0.202
Depression score	12.73±11.12	7.12±5.60	8.938	0.004 *
UPDRS	46.27±16.62	37.26±15.08	7.580	0.007 *

Analysis of variance of factorial design was used. Bonferroni correction was performed. *𝑃<0.05 (depression and UPDRS score). PD: Parkinson’s disease; UPDRS: the unified Parkinson's disease rating scale.