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Behavioural Neurology
Volume 2015, Article ID 196373, 4 pages
Research Article

Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study

1Department of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAE
2Department of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAE
3Department of Neurology, American University of Beirut Medical Center, Beirut 1107, Lebanon

Received 7 August 2015; Revised 2 October 2015; Accepted 13 October 2015

Academic Editor: Jana Tchekalarova

Copyright © 2015 Taoufik Alsaadi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Depression and anxiety are highly prevalent in patients with epilepsy (PWE), with prevalence rates ranging from 20% to 55%. The cause of this increased rate is multifactorial. Depression and epilepsy are thought to share the same pathogenic mechanism. Anxiety, on the other hand, seems to have a prevalence rate among PWE comparable to, or even higher than, those reported for depression, and it is closely linked to epilepsy. To test this hypothesis, we screened for depression and anxiety 186 and 160 patients attending the epilepsy and MS clinics, respectively, using standardized screening tools to determine the rates of both depression and anxiety, comparing these rates to 186 age, sex matched controls. Among the three groups, only patients with epilepsy were at increased risk of having depression (OR = 1.9), whereas anxiety was not. This finding could point to the shared pathogenic mechanisms hypothesis between depression and epilepsy.