Cognitive Impairments in LRRK2-Related Parkinson’s Disease: A Study in Chinese Individuals

Table 1

General demographic and clinical characteristics of patients with PD.

	S1647T carriers	S1647T noncarriers	(/) values
Sex ratio (M/F)	30/15	25/20	0.280 (1.169)
Age (years)	60.79 ± 10.19	64.04 ± 8.17	0.098 (−1.672)
Education (years)	11.49 ± 4.22	11.31 ± 3.89	0.836 (0.208)
Age at PD onset (years)	55.51 ± 10.14	59.01 ± 8.04	0.073 (−1.814)
Disease duration (years)	5.29 ± 3.96	4.96 ± 3.86	0.691 (0.399)
Onset side (right/left)	34/11	36/9	0.612 (0.257)
Symptom at PD onset (tremor/not tremor)	27/18	26/19	0.830 (0.046)
Axial symptom (yes/no)	29/16	23/22	0.200 (1.640)
UPDRS III	23.34 ± 9.88	23.56 ± 12.71	0.930 (−0.088)
Hoehn and Yahr	2.02 ± 0.72	2.02 ± 0.83	1.000 (0)
L-DOPA dose (mg/d)	379.68 ± 264.27	400.39 ± 222.44	0.689 (−0.402)
Anticholinergic use (yes/no)	32/13	35/10	0.468 (0.526)