Cognitive Impairment and Brain Imaging Characteristics of Patients with Congenital Cataracts, Facial Dysmorphism, Neuropathy Syndrome

<div>Patient number 7: a 13-year-old boy with severity score 7. (a) Coronal FLAIR image demonstrates dilated subarachnoid spaces, periventricular dense rim, and dense subcortical and periventricular foci in frontal lobes. (b), (c) Axial T2W image shows bilateral frontal subcortical hyperintensities (dense: 2 points), dilatation of subarachnoid spaces, and no significant dilatation of ventricular system (severity of global brain atrophy: 1 point).</div>

Behavioural Neurology

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Figure 2

Figure 2: Cognitive Impairment and Brain Imaging Characteristics of Patients with Congenital Cataracts, Facial Dysmorphism, Neuropathy Syndrome 