Isoflavone Attenuates the Caspase-1 and Caspase-3 Level in Cell Model of Parkinsonism

Table 1

MTT assay of cell viability and optical density of TH positive PC12 cells.

Group	Cell viability	Optical density of TH positive PC12 cells
Control	0.49 ± 0.11	0.22 ± 0.07
MPP^+	0.30 ± 0.07^**	0.10 ± 0.03^**
I (isoflavone)	0.61 ± 0.17^*	0.46 ± 0.06^*
I + MPP^+	0.56 ± 0.16	0.24 ± 0.04
Z-YVAD-CHO + MPP^+	0.59 ± 0.17^***	0.22 ± 0.05^***
Z-DEVD-CHO + MPP^+	0.60 ± 0.11^***	0.23 ± 0.02^***

compared with isoflavone + MPP⁺; compared with control; compared with MPP⁺.