Isoflavone Attenuates the Caspase-1 and Caspase-3 Level in Cell Model of Parkinsonism

Table 2

Apoptosis rate (%) of PC12 cells.

Group	Apoptosis rate (%)	Necrosis rate (%)	Alive rate (%)
Control	31.3 ± 3.6	3.6 ± 0.3	65.1 ± 4.3
MPP^+	63.5 ± 3.1^**	4.3 ± 0.4	32.2 ± 3.4
Isoflavone (I)	11.5 ± 2.8^*	0.8 ± 0.2	87.7 ± 3.8
I + MPP^+	33.6 ± 3.7	5.1 ± 1.6	61.3 ± 5.6
Z-YVAD-CHO + MPP^+	34.2 ± 1.8^***	3.8 ± 0.7	61.0 ± 4.1
Z-DEVD-CHO + MPP^+	35.6 ± 2.5^***	4.0 ± 0.2	60.4 ± 3.7

compared with isoflavone + MPP⁺; compared with Control; compared with MPP⁺.