Behavioural Neurology / 2015 / Article / Tab 2

Research Article

Isoflavone Attenuates the Caspase-1 and Caspase-3 Level in Cell Model of Parkinsonism

Table 2

Apoptosis rate (%) of PC12 cells.

GroupApoptosis rate (%)Necrosis rate (%)Alive rate (%)

Control31.3 ± 3.63.6 ± 0.365.1 ± 4.3
MPP+63.5 ± 3.1**4.3 ± 0.432.2 ± 3.4
Isoflavone (I)11.5 ± 2.8*0.8 ± 0.287.7 ± 3.8
I + MPP+ 33.6 ± 3.75.1 ± 1.661.3 ± 5.6
Z-YVAD-CHO + MPP+ 34.2 ± 1.8***3.8 ± 0.761.0 ± 4.1

Z-DEVD-CHO + MPP+35.6 ± 2.5***4.0 ± 0.260.4 ± 3.7

compared with isoflavone + MPP+; compared with Control; compared with MPP+.

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