Biomarkers of Eating Disorders Using Support Vector Machine Analysis of Structural Neuroimaging Data: Preliminary Results
Table 1
Demographic characteristics.
Variables
ED ()
HC ()
-level
Demographical data
Age (years)
30.2 ± 5.6
30.1 ± 5.5
0.95
Educational level (years)
17 (13–21)
17 (13–21)
0.88
BMI
23.6 ± 8.2
24.1 ± 4.8
0.79
MRI data
Total GM Volume
587.3 ± 37.5
608.88 ± 42.1
0.11
Total WM Volume
486.5 ± 63.1
489.6 ± 41.6
0.86
Total CSF Volume
188.3 ± 28.7
187 ± 23.2
0.88
Clinical data
HAMA
14.6 ± 13
4 ± 2.2
0.04
BDI
16.8 ± 10.1
6.3 ± 4.7
0.0004
DES
14.32 ± 12.4
5.12 ± 4
0.007
EAT-26
23.3 ± 14.4
6.35 ± 3.2
0.00004
SDQ-20
28.64 ± 14.8
20.6 ± 1.1
0.03
BIDA
29.9 ± 19.4
19.9 ± 11
0.24
Clinical data EDI-2 scale
Drive for thinness
9.4 ± 6.3
1.2 ± 1.3
0.0001
Bulimia
3.47 ± 4.5
0.1 ± 0.5
0.01
Interoceptive awareness
7.9 ± 6.2
0.7 ± 1.2
0.0006
Asceticism
5.6 ± 3.8
2 ± 1.1
0.0006
Body dissatisfaction
12.9 ± 7.2
6.1 ± 2.9
0.001
Perfectionism
4.3 ± 3.9
3.3 ± 3.1
0.41
Interpersonal distrust
3.6 ± 3.1
1.4 ± 1.2
0.04
Impulse regulation
3.67 ± 4.9
0.6 ± 1.4
0.02
Ineffectiveness
3.5 ± 5.2
1.2 ± 2.6
0.12
Maturity fears
5.2 ± 3
3.94 ± 2.6
0.13
Social insecurity
3.53 ± 3.2
2.1 ± 2
0.22
Data are given as mean values (SD) or median values (range) when appropriate. BMI: Body Mass Index; GM: gray matter; WM: white matter; CSF: cerebrospinal fluid; PBI: parental bonding instrument; STAI: State-Trait Anxiety Inventory; HAMA: Hamilton rating scale for anxiety; BDI: Beck Depression Inventory; DES: Dissociative Experiences Scale; EAT-26: eating attitude test-26; SDQ-20: Somatoform Dissociation Questionnaire-2; BIDA: Body Image Dimensional Assessment; EDI-2: Eating Disorder Inventory-2. Total brain MRI parameters have been calculated using VBM8 tool. Significant difference.
