The Effect of Task-Irrelevant Fearful-Face Distractor on Working Memory Processing in Mild Cognitive Impairment versus Healthy Controls: An Exploratory fMRI Study in Female Participants

Figure 2

Plots of mean percent change in brain activity within a priori regions of interest in response to high-loading WM task during fearful-face distractors in MCI and HC subjects. Group mean % signal change average over all voxels within regions defined a priori from anatomical brain masks. Significant group differences were observed in the amygdala (AMY) (). ACC: anterior cingulate cortex; PFC: prefrontal cortex; PAR: superior parietal gyrus.