Review Article

Pain in Neurodegenerative Disease: Current Knowledge and Future Perspectives

Table 1

Summary of the studies on the prevalence of pain among patients with dementia living at home or in nursing homes. Features and location of pain were not available.  

Study designNumber of patients and controlsAssessment methodFrequency of pain

Barry et al. [7]ObservationalPatients: 75  
Controls: 0
Interview with patients and caregiversDaily pain
Patients’ report: 57% 
Caregivers’ report: 71%

Barry et al. [8]Observational Patients: 42  
Controls: 0
Interview with patients, nurses, and relativesDaily pain
Patients’ report: 38% 
Nurses’ report: 69% 
Relatives’ report: 75%

Hunt et al. [9]ObservationalPatients: 802  
Controls: 802
Interview with patientsBothersome pain
Patients’ report: 64% 
Controls’ report: 55%

Werner et al. [10]ObservationalPatients: 141 
Controls: 55
Category rating scalePain is experienced
Patients’ report: 21% 
Patients’ and Caregivers’ report: 46% 
Controls’ report: 48.1

Mäntyselkä et al. [11]ObservationalPatients: 75 
Controls: 446
Interview with the patientsAny pain
Patients’ report: 43% 
Controls’ report: 69%

Shega et al. [12]ObservationalPatients: 150 
Controls: 0
Interview with patients and caregiversPain right now
Patients’ report: 32% 
Caregivers’ report: 52%

Zwakhalen et al. [13]ObservationalPatients: 117 
Controls: 0
Observational pain scaleExperience of pain to some extent
Nurses’ observations: 47%