Research Article

Laser Evoked Potentials in Early and Presymptomatic Huntington’s Disease

Table 1

Demographic and clinical data in normal subjects (N), Huntington’s disease (HD) patients, and presymptomatic Huntington’s disease (PHD) patients. The ANOVA analysis shows that age was different among groups. TFC score: total functional capacity score; UHDRS: Unified Huntington’s Disease Rating Scale; MMSE: Mini-Mental State Examination. The CAG range is reported. For time from or before illness onset, the range is reported in parentheses. In PHD, negative values indicate the supposed years before clinical HD diagnosis.

AgeSexCAGIllness onset (years) UHDRS motor sectionTFC scoreMMSEChronic pain (number)

N42 ± 16.3534 F
30 M

HD54 ± 11.5020 F
22 M
39–563.23 ± 2.11 (1,5)32.93 ± 18.978.92 ± 3.3327.1 ± 1.83
(mixed pain (2) and fibromyalgia syndrome (1))

PHD36.62 ± 8.615 F
5 M
39–51−12.20 ± 9.6
(−1, −21)
4.1 ± 4.3313 ± 029.9 ± 0.310

ANOVA 

Chi square: 0.99 ns