Mice with Catalytically Inactive Cathepsin A Display Neurobehavioral Alterations

Figure 4

Learning and memory is impaired in 12-month-old mice. Comparison of Morris water maze test results for mice and their wild-type littermates at 12 months of age. (a) Average escape latency. (b) Distance travelled before reaching the platform. (c) Proximity of mice to target in the visible (days 1–3) and in the hidden platform (days 4–8) tests. Graph shows average time or distance ± SEM.

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