Neuroprotective and Antiamnesic Effects of Mitragyna inermis Willd (Rubiaceae) on Scopolamine-Induced Memory Impairment in Mice

Table 3

Effect of M. inermis in normal mice in ORT.

Treatments	Exploration time (seconds)			Discrimination index
	Session 1	Session 2
		N	F
H2O	36.0 ± 4.5	25.2 ± 1.5	15.0 ± 1.6	0.25
39.3	39.8 ± 3.8	31.8 ± 2.2	11 ± 1	0.48
98.25	39.8 ± 3.7	31.2 ± 3.1	10.2 ± 0.83	0.51
196.5	36.2 ± 1.3	33.4 ± 2.6	9.4 ± 0.9	0.56
393	38.4 ± 2.4	32.6 ± 2.1	10.6 ± 0.9	0.51
Pira	34.8 ± 4.2	33.2 ± 1.9	9.6 ± 1.1	0.55

Data are mean ± SD, per dose. , , and , compared to control group (H2O), one-way ANOVA followed by Dunnett’s bilateral comparisons for exploration time, and Duncan’s test for discrimination index. F: familiar object, H2O: distilled water, N: novel object, Pira: piracetam 200 mg/kg.