Behavioural Neurology

Research Article

Neuroprotective and Antiamnesic Effects of Mitragyna inermis Willd (Rubiaceae) on Scopolamine-Induced Memory Impairment in Mice

Table 6

Chemical evaluation of CAT, SOD, and MDA activities.


Treatments	CAT (mmol H₂O₂/mg protein)	SOD (units/mg protein)	TBARS (mmol/mg protein)

H2O + Scop	58.6 ± 4.6^c	0.8 ± 0.2^c	1.3 ± 0.2^b
39.3 + Scop	115.8 ± 1.1	2.4 ± 0.12	0.8 ± 0.1
98.25 + Scop	251.4 ± 32.6	5.1 ± 0.5	0.6 ± 0.1
196.5 + Scop	274.4 ± 8.8	4.9 ± 0.2	0.6 ± 0.1
393 + Scop	325.0 ± 18.9	6.4 ± 0.4	0.6 ± 0.1
Pira + Scop	179.2 ± 9.0	4.7 ± 0.3	0.7 ± 0.1
H2O + H2O	244.5 ± 10.9	6.7 ± 0.2	0.6 ± 0.1

Data are mean ± SEM, per dose. , , and as compared with scopolamine-treated group (H2O + Scop), one-way ANOVA followed by Duncan’s test; ^b, ^c compared to the normal control group (H2O + H2O), one-way ANOVA followed by Duncan’s test. Pira: piracetam, H2O: distilled water, CAT: catalase, SOD: superoxide dismutase, TBARS: thiobarbituric acid reactive substance activity.