Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats

Figure 4

Graphic representation of the number of entries (a and b) and percentage of spontaneous alternances (c and d) before and after scopolamine exposition in rats treated with different substances into the Y-maze. SHAM 1 = sham-operated rats treated with vehicle as normal control 1; SHAM 2 = sham-operated rats treated with vehicle as normal control 2; OVX = ovariectomized rats treated with vehicle as negative control; PIR = ovariectomized rats treated with piracetam at the dose of 1.5 mg/kg BW as positive control 1; E2V = ovariectomized rats treated with estradiol valerate at the dose of 1 mg/kg BW as positive control 2; FU 50 and 200 = ovariectomized rats treated with F. umbellata aqueous extract at the doses of 50 and 200 mg/kg BW, respectively; MC = ovariectomized rats treated with 7-methoxycoumarin at the dose of 1 mg/kg BW. SCOP = animal that received a single dose of scopolamine (2 mg/kg BW). as compared to the SHAM 1 group; as compared to the SHAM 2 group; , , and as compared to the OVX group.

(a)

(b)

(c)

(d)