Delusions in Patients with Dementia with Lewy Bodies and the Associated Factors

Table 1

Demographic and background characteristics between the delusional and nondelusional patients with DLB.

	Delusional	Nondelusional		p
N	106	101
Gender, male/female	53/53	62/39	2.716	NS
Age, years (SD, range)	78.9 (6.8, 62–91)	77.6 (6.8, 51–90)	−1.301	NS
Education, years (SD, range)	5.8 (5.2, 0–18)	6.6 (5.0, 0–19)	−1.047	NS
Duration, years (SD, range)
Dementia	3.0 (3.0, 0–20)	2.8 (2.8, 0–15)	0.358	NS
Parkinsonism	3.0 (3.0, 0–20)	2.6 (2.3, 0–10)	1.019	NS
Psychiatric disorder	4.0 (5.1, 0–40)	3.2 (3.6, 0–25)	1.251	NS
RBD	5.0 (9.5, 0–50)	5.5 (11.0, 0–50)	−0.225	NS
DLB probable/possible	79/27	61/40	4.719	0.030
CDR 0.5/1/2–3	10/38/58	25/42/32	12.776	0.002
CDR-SB (SD, range)	9.3 (3.3, 1.5–17.0)	7.5 (3.8, 1.5–16.0)	3.779	<0.001
MMSE (SD, range)	14.0 (7.0, 0–29)	16.9 (8.0, 0–29)	−2.623	0.009
CASI (SD, range)	44.7 (23.1, 0–95)	53.7 (25.9, 0–94)	−2.629	0.009
NPI (SD, range)	34.3 (14.6, 3–77)	19.4 (15.4, 0–79)	7.144	<0.001
NPI burden (SD, range)	17.9 (6.7, 0–32)	9.1 (5.8, 0–25)	10.113	<0.001
UPDRS-m (SD, range)	17.7 (11.3, 0–63)	18.1 (11.4, 0–48)	−0.279	NS
Antipsychotics, n (%)	22 (20.8%)	12 (11.9%)	2.967	NS
Antiparkinsonian, n (%)	41 (38.7%)	42 (41.6%)	0.182	NS
LED (SD, range)	146 (237, 0–1050)	181 (276, 0–1158)	0.977	NS

NS: not significant; DLB: dementia with Lewy bodies; RBD: REM sleep behavior disorder; psychiatric disorder: psychosis or mood disorders; DLB probable/possible: diagnosis of probable DLB/possible DLB; CDR: Clinical Dementia Rating scale; CDR-SB: sum of boxes of CDR; MMSE: Mini-Mental State Examination; CASI: Cognitive Abilities Screening Instrument; NPI: total score of the 12-domain Neuropsychiatric Inventory; NPI burden: total caregiver burden scale in the NPI; UPDRS-m: motor score of the Unified Parkinson’s Disease Rating Scale; antipsychotics: current using antipsychotics; antiparkinsonian: current use of antiparkinsonian agents; LED: levodopa equivalent dose, mg/day.