Delusions in Patients with Dementia with Lewy Bodies and the Associated Factors
Table 4
Two models of risk estimates (odds ratios) for neuropsychiatric symptoms in the NPI between the delusional and nondelusional DLB groups.
Neuropsychiatric symptoms
Mean (SD, range)
Model 1
Model 2
Delusional
Nondelusional
OR (95% CI)
p
OR (95% CI)
p
N
106
101
Hallucinations
71 (67.0%)
37 (36.6%)
3.27 (1.83–5.85)
<0.001
2.59 (1.39–4.80)
0.003
Agitation
52 (49.1%)
30 (29.7%)
2.40 (1.34–4.30)
0.003
1.87 (1.01–3.48)
0.048
Depression
76 (71.7%)
65 (64.4%)
1.31 (0.72–2.38)
NS
1.19 (0.64–2.22)
NS
Anxiety
72 (67.9%)
45 (44.6%)
2.49 (1.40–4.43)
0.002
2.64 (1.45–4.81)
0.002
Euphoria
2 (1.9%)
2 (2.0%)
1.22 (0.14–9.02)
NS
0.62 (0.77–4.96)
NS
Apathy
72 (67.9%)
59 (58.4%)
1.58 (0.88–2.82)
NS
1.26 (0.68–2.32)
NS
Disinhibition
24 (22.6%)
5 (5.0%)
5.28 (1.91–14.44)
<0.001
4.81 (1.71–13.53)
0.003
Irritation
62 (58.5%)
24 (23.8%)
4.85 (2.62–8.99)
<0.001
4.50 (2.39–8.46)
<0.001
Aberrant motor behavior
50 (47.2%)
23 (22.8%)
2.93 (1.59–5.38)
0.001
2.36 (1.23–4.51)
0.01
Sleep
91 (85.8%)
78 (77.2%)
1.72 (0.83–3.55)
NS
1.56 (0.74–3.30)
NS
Eat/appetite
47 (44.3%)
30 (29.7%)
1.54 (0.87–2.74)
NS
1.36 (0.75–2.46)
NS
DLB: dementia with Lewy bodies; NPI: Neuropsychiatric Inventory; NS: not significant. The odds ratio (OR) and 95% confidence interval (CI) were calculated with the nondelusional group as reference. Model 1 ORs were adjusted for age and gender; model 2 ORs were adjusted for age, gender, disease severity, antipsychotics, and antiparkinsonian agents.
