Dynamic Evaluation of Notch Signaling-Mediated Angiogenesis in Ischemic Rats Using Magnetic Resonance Imaging

Figure 1

Experimental design. Forty rats were subjected to 90 minutes of transient middle cerebral artery occlusion (tMCAO) and then treated with PBS or DAPT at 3 days after ischemia. MRI was performed at 24 hours and weekly up to 4 weeks, after which four rats of each group were decapitated, respectively, for IF.