Research Article

Polysomnographic Findings in Fragile X Syndrome Children with EEG Abnormalities

Table 1

Comparison between fragile X syndrome (FXS) and typical developing children (TDC) for polysomnographic macrostructural parameters. This table shows the differences between fragile X syndrome (FXS) and typical developing children (TDC) for polysomnographic macrostructural parameters: interquartile range (IQR); time in bed (TIB-min); sleep partial time (SPT-min); total sleep time (TST-min); sleep onset latency (SOL-min); first REM latency (FRL-min); stage shifting/h (SS-h); awakenings per hour (AWN-h); sleep efficiency percentage (SE%); wake after sleep onset percentage (WASO%); N1, N2, and N3 stage percentages; arousal indexes during the NREM and REM periods; apnea/hypopnea index (AHI); oxygen desaturation index (ODI); oxygen saturation (SpO2); nadir and desaturation percentage levels; and periodic limb movement index (PLMI).

FXS ()TDC ()
MedianIQRMedianIQR value

TIB-min497454-539584519-655-3.7970.0001
SPT-min502453-522.5545485-609.5-3.1570.001
TST-min409.5409.5-437516462-575-5.683<0.0001
SOL-min15.2-27.5-4819.58-37.5-0.5620.57
FRL-min90.590.5-90.511681-150-1.4690.14
SS-h7.25.3-9.58.35.3-11.5-0.8390.401
AWN-h7.45.6-9.61.4811.50.5- 3.2<0.0001
SE%81.26176.160-90.31290.186.6-94.9-2.9320.003
WASO%16.50515.745-17.0824.70.9-7.75.701<0.0001
N1%3.0272.927-3.1311.40.7-4.21.5490.121
N2%29.76025.847-31.06839.531.6-44.9-4.299<0.0001
N3%27.58926.507-30.13029.824.1-35.9-0.4760.634
REM%23.00121.078-26.51121.416.2-26.11.4100.15
NREM arousal index5.6444.818-6.8176.6455.616-7.372-2.3790.01
REM arousal index9.4598.858-10.0158.6357.824-9.4292.6380.008
AHI9.8899.461-10.6140.4480.7650.528-1.069<0.0001
ODI4.1393.92-4.9210.469015-0.8636.306<0.0001
SpO2%93.90492.156-94.34598.40397.889-98.902-6.306<0.0001
SpO2 nadir%89.97789.148-91.17996.48996.282-97.069-6.306<0.0001
SpO2 desat%7.7437.057-8.4683.4762.767-3.8626.306<0.0001
PLMI6.4235.256-7.6592.9122.393-3.4576.237<0.0001