Research Article

Polysomnographic Findings in Fragile X Syndrome Children with EEG Abnormalities

Table 2

Comparison between fragile X syndrome (FXS) with EEG abnormalities (IEDs) and without EEG anomalies (NIEDs) for polysomnographic macrostructural parameters. This table shows the differences between fragile X syndrome (FXS) children with interictal epileptiform discharges (IEDs) and without them (NIEDs) for polysomnographic macrostructural parameters: interquartile range (IQR); time in bed (TIB-min); sleep partial time (SPT-min); total sleep time (TST-min); sleep onset latency (SOL-min); first REM latency (FRL-min); stage shifting/h (SS-h); awakenings per hour (AWN-h); sleep efficiency percentage (SE%); wake after sleep onset percentage (WASO%); N1, N2, and N3 stage percentages; arousal indexes during the NREM and REM periods; apnea/hypopnea index (AHI); oxygen desaturation index (ODI); oxygen saturation (SpO2); nadir and desaturation percentage levels; and periodic limb movement index (PLMI).

FXS IEDs ()FXS NIEDs ()
MedianIQRMedianIQR value

TIB-min499459.2-539493444.3-535.2-0.7280.46
SPT-min518505-529474.75405-500.5-3.2520.001
TST-min432.5419.5-444411.25319.5-422-3.0580.002
SOL-min-1-59-15.535.3914-69.52.1350.03
FRL-min90.590.5-11290.590.5-1141.3960.16
SS-h6.25.3-7.99.456.2-10.81.7740.07
AWN-h6.85.2-8.37.65.8-10.51.1660.24
SE%83.7080.45-94.3677.5771.93-84.15-1.9410.05
WASO%16.5016.14-16.9316.5210.01-17.08-0.1940.84
N1%2.992.92-3.063.1032.95-4.6251.6020.10
N2%30.0129.36-30.7927.7623.74-31.06-0.9220.35
N3%26.7326.15-27.4229.1927.67-32.663.3000.001
REM%23.7421.78-25.4022.2920.86-27.70-0.580.56
NREM arousal index5.384.79-6.815.754.83-6.750.240.80
REM arousal index9.639.01-10.139.348.38-9.84-1.1650.24
AHI10.239.64-10.619.769.04-10.040.9220.35
ODI4.324.08-4.824.053.48-4.92-1.210.22
SpO2%94.2293.53-94.5692.5891.87-94.03-2.230.02
SpO2 nadir%90.5089.65-91.1789.9189.13-90.90-0.7760.43
SpO2 desat%7.426.97-8.467.827.23-8.240.7280.46
PLMI5.835.06-6.816.766.01-7.961.2130.22