Behavioural Neurology / 2019 / Article / Tab 1

Review Article

Nonpharmacologic Interventions for the Self-Management of Anxiety in Parkinson’s Disease: A Comprehensive Review

Table 1

Self-managed nonpharmacologic anxiety studies.

AuthorsStudy designStudy aim or purposeInterventionControlSample sizeAnxiety toolStatistical significance: yes/no
TreatmentControl

Experimental
Dobkin et al. [33]RCTSecondaryTailored CBTUsual care4139HAM-AYes
Craig et al. [35]RCTSecondaryListening to relaxing musicNMT1814BAIYes
Sajatovic et al. [30]RCTSecondarySelf-managed program + exerciseExercise1212COVINo
Advocat et al. [38]RCTSecondaryMindfulness-based lifestyle classesWaitlist2433DASS-21No
Veazey et al. [40]RCTSecondaryTelephone or in-person CBTUsual Care43BAINo
Quasi-experimental
Dobkin et al. [41]Uncontrolled intervention pilot studySecondaryTelephone-based CBT20HAM-AYes
Troeung et al. [42]Nonrandomized interventionPrimaryPD-specific CBT18DASS-21Yes
Berardelli et al. [43]Nonrandomized interventionOutcomeGroup CBT classes7HAM-AYes
Dissanayaka et al. [70]Uncontrolled mixed-methodfeasibility studyPrimaryTailored mindfulness-basedCT14GAIYes
Dissanayaka et al. [46]Uncontrolled intervention studyPrimaryTailored CBT (dyad of pts & caregivers)12 = patientsGAI
HAM-A
IQAD
No/yes/yes
Yes (all times)
No (all times)
10 = caregivers
Dobkin, Allen, & Menza [48]Uncontrolled intervention pilotOutcomeModified & individualized CBT13STAINo
Calleo et al. [50]Nonrandomized intervention studySecondaryIndividualized, telephone, or in-person CBTPatients = 8 telephone
8 in-person
SIGH-ANo
Caregivers = 4 telephone
2 in-person
Shinmei et al. [53]Uncontrolled feasibility studySecondaryCulturally adapted CBT18HADSNo

Note: RCT = randomized controlled trials; N = number; Tx = treatment; NMT = neuromuscular therapy; CBT = cognitive-based therapy; BAI = Beck Anxiety Inventory; HAM-A = Hamilton Anxiety Measure; COVI = Covi Anxiety Scale; DASS-21 = Depression Anxiety Stress Scale-21; GAI = Geriatric Anxiety Inventory; IQAD = Informant Questionnaire for Anxiety in Dementia; STAI = Spielberger State-Trait Anxiety Inventory; SIGH-A = Structured Interview Guide for HAM-A; HADS = Hospital Anxiety and Depression Scale; OASIS = Overall Anxiety Severity and Impairment Scale.

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