Research Article

Frontal Anatomical Correlates of Cognitive and Speech Motor Deficits in Amyotrophic Lateral Sclerosis

Table 3

Comparisons of SABRE-generated regional volumes by tissue class between patients with ALS and controls. Only statistically significant results are presented (). SD: standard deviation; GM: grey matter; WM: white matter; CSF: cerebrospinal fluid; L: left; R: right.

Region, tissue classALS
(mean, SD)
Controls
(mean, SD)
statistic value

Precentral, WM, L36.21, 4.6541.44, 5.192360.020
Precentral, CSF, L23.46, 6.4517.45, 4.371190.012
Precentral, CSF, R23.17, 7.2117.28, 2.751230.019
Postcentral, CSF, L22.17, 5.5417.67, 2.731300.037
Postcentral, GM, R37.53, 3.8740.14, 2.522280.045
Superior frontal, GM, L46.18, 5.8452.62, 2.802580.002
Superior frontal, WM,L20.40, 4.3124.05, 4.162270.049
Superior frontal, CSF, L33.40, 8.3123.32, 4.541070.003
Superior frontal, GM, R46.12, 7.9951.43, 3.462400.014
Superior frontal, WM, R19.33, 7.8023.80, 3.082280.045
Superior frontal, CSF, R34.55, 12.0024.76, 3.941250.023
Medial Sup frontal, GM, L40.10, 5.6544.78, 3.312290.041
Medial Sup frontal, WM, R21.20, 5.7625.57, 3.102310.034
Medial Sup frontal, CSF, R36.84, 10.4028.52, 4.671300.037