A Novel PRRT2 Variant in Chinese Patients Suffering from Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsion
Table 2
Statistical analysis and clinical correlations.
Variable
Total
PRRT2-VE
Correlation
value
Age of onset
Mean (SD)
8 y (1.318)
8.6 y (1.924)
5 y (2.775)
-0.3675
0.07958
Median
6 y
2 y
5 y
—
—
Gender
Male
(%)
6 (46%)
5 (50%)
1 (33.3%)
-0.4158
0.2656
Female
7 (53.8%)
5 (50%)
2 (66.6%)
0.68047
0.3504
Origin (Chinese)
(%)
13 (100%)
10 (77%)
3 (23%)
-0.3675
0.07958
Family history of PKD
(%)
9 (69%)
8 (61.5%)
1 (7.7%)
-0.395563
0.0268
History of involuntary movement
(%)
7 (53.8%)
5 (3.8%)
2 (15.3%)
-0.854242
0.0131
Duration of attack(s)
Mean Median
15 s 20 s
12.6 20 s
23.3 s 35 s
0.427347
0.0225
Frequency of attacks
1-5 per day
(%)
5 (38.4%)
5 (50%)
0 (0%)
—
—
1-5 per week
1 (07%)
0 (0%)
1 (33.3%)
—
—
1-5 per month
5 (38.4%)
4 (40%)
1 (33.3%)
-0.5222
0.12103
Statistical analysis indicates that the significant difference is between positive and negative PKD patients at 0.05 significant level and there is no correlation observed between different variant samples of positive and negative PKD patients.
