Research Article

Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia

Table 2

Comparison of the voice parameters used between older people with nondegenerative MCI and those expected to develop AD. Mann-Whitney test of independent samples and means of the two groups.

ParametersnodMCI mean (SD)preAD mean (SD)Mann-Whitney (standardised test)

Duration parameters
 Duration (reading time)47.48 (22.20)61.74 (20.95)243 (-2.791)
 Phonation time (sec)32.35 (10.39)39.44 (8.75)213 (-3.153)
 Speech rate3.35 (0.80)3.07 (0.92)583 (1.308)
 Pauses number25.79 (16.34)34.23 (14.64)283 (-2.310)
Speech fluency and rhythm parameters
 Normalized_PVI54.27 (5.42)59.97 (5.76)215 (-3.128)
 Syll_Interv_DAverage0.19 (0.03)0.20 (0.02)416 (-0.705)
 Syll_Interv_ΔStandar0.10 (0.02)0.11 (0.02)246 (-2.755)
 VARCO of syllabic interval duration0.51 (0.07)0.55 (0.09)349 (-1.513)
 Syllabus interval number154.01 (51.88)178.08 (33.94)223 (-3.033)
 Articulation rate4.63 (0.59)4.54 (0.60)519 (0.537)
Fundamental frequency and spectral analysis
 F0 mean (Hz)168.61 (28.90)164.82 (20.21)514 (0.476)
 F0 mean (Hz_men)138.86 (25.17)138.84 (16.31)41 (0.077)
 F0 mean (Hz_women)172.12 (16.34)170.09 (13.73)250 (0.230)
 Asymmetry (skewness, Hz)11.33 (4.14)8.62 (4.38)645 (2.056)
 Center of gravity (CoG_Hz)446 (98)568 (227)321 (-1.851)
 Center of gravity SD (CoG_sd)547 (191)753 (318)276 (-2.393)
 LTAS mean (dB)32.46 (2.31)30.20 (2.00)763 (3.478)
  LTAS mean (dB_men)32.41 (2.64)30.47 (2.33)30 (-0.878)
  LTAS mean (dB_women)32.48 (2.20)30.07 (1.97)401 (3.247)
 LTAS SD (dB)40.32 (2.10)38.16 (2.82)738 (3,177)
  LTAS SD (dB_men)40.21 (2.31)38.46 (3.08)57 (1.317)
  LTAS SD (dB_women)40.37 (2.03)38.03 (2.88)388 (2.987)
 LTAS range 50-1000 Hz44.87 (2.03)43.26 (2.37)694 (2.646)
  LTAS range 50-1000 Hz_men46.24 (2.12)44.76 (3.27)51 (0.852)
  LTAS range 50-1000 Hz_women46.40 (2.06)43.98 (4.12)369 (2.608)
 LTAS 1 kHz-2 kHz27.13 (3.29)26.21 (4.98)513 (0.464)
 LTAS 2 kHz-4 kHz17.87 (4.59)17.94 (2.98)480 (0.066)
Intensity parameters
 Intensity mean (dB)75.36 (1.77)73.63 (2.00)735 (3.141)
  Intensity mean (dB_men)74.94 (0.41)73.94 (0.91)55 (1.162)
  Intensity mean (dB_women)75.98 (0.41)73.51 (0.60)390 (3.027)
 Intensity mean_SD (dB)17.28 (10.54)14.77 (2.94)551 (0.922)
  Intensity SD (dB_men)19.24 (14.31)12.76 (4.26)51 (0.852)
  Intensity SD (dB_women)16.55 (8.78)15.66 (1.79)198 (-0.809)
 Amplitude minimum-9.08 (13.53)25.01 (12.44)551 (0.922)
  Intensity Minim (dB_men)-23.19 (129.34)27.59 (14.61)46 (0.465)
  Intensity Minim (dB_women)-3.76 (107.83)23.85 (12.14)285 (0.929)
 Intens Diferenc Max-Min Mean (dB)95.55 (13.40)61.76 (12.26)377 (-1.175)
  Intens Dif Max-Min (dB_men)109.22 (129.34)58.79 (14.07)34 (-0.465)
  Intens Dif Max-Min (dB_women)90.37 (107.68)63.07 (12.03)181 (-1.149)
Acoustic Voice Quality parameters
 Jitter (local)2.42 (1.07)2.35 (0.66)427 (-0.567)
 Shimmer Loc (dB)1.12 (0.27)1.19 (0.22)394 (-0.965)
 Voice breaks (%)38.93 (11.01)43.93 (13.24)333 (-1.706)
 Acoustic Voice Quality Index (AVQI)6.00 (1.18)6.17 (0.95)425 (-0.597)
 HNR (dB)12.96 (3.50)11.91 (3.18)570 (1.151)

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