Anatomical Covariance Analysis: Detection of Disrupted Correlation Network Related to Clinical Trait Fatigue in Multiple Sclerosis: A Pilot Study

Table 1

Demographic and clinical information of the sample.

Variable	nF-MS group ()	F-MS group ()	value
	M (SD)	M (SD)
Age	45.5 (10.9)	49.5 (8.8)	n.s.
Gender/male, (%)	2 (20%)	1 (10%)	n.s.
Education	15.3 (1.8)	16.3 (2.6)	n.s.
Disease duration (months)	118.8 (56.1)	198.1 (122.3)	n.s.
MS type, (%)
RRMS	5 (62.5%)	7 (77.8%)
PPMS	1 (12.5%)	0	n.s.
SPMS	2 (25%)	1 (11.1%)
PRMS	0	1 (11.1%)
FSS	31.2 (5.5)	59.0 (3.37)	<0.005
VAS_F	8.7 (9.8)	26.5 (25.2)	0.059
SDMT, raw scores	51.5 (16.2)	50.8 (11.6)	n.s.

MS: multiple sclerosis; RRMS: Relapsing-Remitting MS; PPMS: Primary Progressive MS; SPMS: Secondary Progressive MS; PPRMS: Progressive Primary Relapsing MS; FSS: Fatigue Severity Scale; VAS_F: Visual Analogue Scale for Fatigue; SDMT: Symbol Digit Modality Test; M: mean; SD: (standard deviation); : number. See [22] for the MS type diagnosis criteria.