Research Article

Anatomical Covariance Analysis: Detection of Disrupted Correlation Network Related to Clinical Trait Fatigue in Multiple Sclerosis: A Pilot Study

Table 3

Bivariate transhemispheric correlations between the different VOIs from the CoStN.
(a)

nF-MS group

Left
RightICACCThal.Put.PCCCaud.Amyg.
IC0.66 (0.04)n.s.n.s.n.s.n.s.n.s.n.s.
ACCn.s.0.74 (0.02)-0.88 (0.00)-0.93 (0.00)n.s.-0.78 (0.01)n.s.
Thal.n.s.-0.81 (0.01)0.92 (0.00)0.71 (0.02)n.s.0.99 (0.03)-0.67 (0.04)
Put.n.s.n.s.0.82 (0.00)0.96 (0.00)n.s.0.78 (0.00)n.s.
PCCn.s.0.76 (0.01)n.s.n.s.0.91 (0.00)n.s.n.s.
Caud.n.s.n.s.0.72 (0.02)0.79 (0.01)n.s.0.94 (0.00)n.s.
Amyg.n.s.n.s.n.s.n.s.n.s.n.s.0.85 (0.00)

(b)

F-MS group

Left
RightICACCThal.Put.PCCCaud.Amyg.
IC0.98 (0.00)n.s.n.s.n.s.n.s.n.s.n.s.
ACCn.s.n.s.n.s.n.s.n.s.n.s.n.s.
Thal.n.s.n.s.0.91 (0.00)n.s.n.s.n.s.n.s.
Put.n.s.n.s.n.s.0.86 (0.00)n.s.n.s.0.77 (0.00)
PCCn.s.n.s.-0.64 (0.05)n.s.n.s.n.s.0.72 (0.02)
Caud.n.s.n.s.n.s.n.s.n.s.0.88 (0.00)n.s.
Amyg.n.s.n.s.n.s.n.s.n.s.n.s.0.71 (0.01)

IC: insular cortex; ACC: anterior cingulate cortex; Thal.: thalamus; Put.: putamen; PCC: posterior cingulate cortex; Caud.: caudate; Amyg.: amygdala. The first number refers to the correlation’s coefficient; the second number between parentheses refers to the significance of the correlation.