Upper and Lower Limb Motor Function Correlates with Ipsilesional Corticospinal Tract and Red Nucleus Structural Integrity in Chronic Stroke: A Cross-Sectional, ROI-Based MRI Study

Table 1

Nonparametric correlations between motor function and mean FA values in a priori ROIs.

FA in a priori ROIs	Behavioral measures
	BBTAff ()†	GripAff ()†	Arm MIAff ()†	Leg MIAff ()†	Gait speed ()†
Ipsilesional
CST	0.55 ()	0.38 ()	0.52 ()	0.44 ()	0.35 ()
Body of CC	0.05 ()	-0.25 ()	0.12 ()	-0.03 ()	-0.27 ()
Red nucleus	0.45	0.36	0.45	0.49	0.50
Thalamus	0.33 ()	0.11 ()	0.39 ()	0.14 ()	-0.12 ()
Substantia nigra	0.36 ()	0.19 ()	0.36 ()	0.37 ()	0.17 ()
SCP	0.10	0.17	0.19	0.26	0.20
Contralesional
CST	0.13	0.23	0.15	0.11	0.11
Body of CC	0.11	-0.05	0.10	0.01	-0.04
Red nucleus	0.01	-0.08	0.06	0.08	0.22
Thalamus	0.02	0.07	0.02	-0.02	-0.19
Substantia nigra	-0.25	-0.24	-0.26	-0.25	-0.15
SCP	0.09	0.26	0.18	0.30	0.36

Values in the table are Spearman’s coefficients (). Abbreviations: ROIs: regions of interest; BBT_Aff: Box and Block Test (affected limb); Grip_Aff: grip strength (affected limb); Arm MI_Aff: Arm Motricity Index score (affected limb); Leg MI_Aff: Leg Motricity Index score (affected limb); CST: corticospinal tract; CC: corpus callosum; SCP: superior cerebellar peduncle. †Overall value ( exceptions noted in parentheses, accounting for ROIs with ≥5% lesion volume). ; .