Research Article
Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder
Table 2
Correlation between SNP genotypes and allele frequencies and childhood ASD.
| | SNPs | Genotype/allele | Cases
(%) | Controls
(%) | OR (95% CI) | value |
| | rs3746599 | A/A | 89 (44.3) | 71 (36.2) | 1 | | | A/G | 80 (39.8) | 99 (50.5) | 0.98 (0.54-1.80) | 0.9526 | | G/G | 32 (15.9) | 26 (13.3) | 0.65 (0.42-0.99) | 0.0449 | | A | 258 (64.2) | 241 (61.5) | 1 | | | G | 144 (35.8) | 151 (38.5) | 0.89 (0.67-1.19) | 0.4314 |
| | rs7794745 | A/A | 60 (29.9) | 77 (38.5) | 1 | | | A/T | 102 (50.8) | 95 (47.5) | 1.38 (0.89-2.14) | 0.1516 | | T/T | 39 (19.4) | 28 (14.0) | 1.79 (0.99-3.23) | 0.0542 | | A | 222 (55.7) | 249 (65.3) | 1 | | | T | 180 (44.3) | 151 (37.7) | 1.34 (1.01-1.77) | 0.0435 |
| | rs251379 | A/A | 45 (22.4) | 40 (20.1) | 1 | | | A/G | 92 (31.8) | 90 (45.2) | 0.83 (0.48-1.42) | 0.4880 | | G/G | 64 (45.8) | 68 (34.7) | 0.91 (0.54-1.52) | 0.7161 | | A | 182 (45.3) | 170 (42.7) | 1 | | | G | 220 (54.7) | 228 (57.3) | 0.90 (0.68-1.19) | 0.4660 |
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OR: odds ratio; CI: confidence interval.
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