Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder

Table 4

Correlation between SNP genotypes and allele frequencies and severity of childhood ASD.

	Genotype/allele	Mild/moderate; (%)	Severe; (%)	OR (95% CI)	value
rs3746599	A/A	50 (41.0)	39 (49.4)	1
	A/G	54 (44.3)	26 (32.9)	0.62 (0.33-1.16)	0.3210
	G/G	18 (14.7)	14 (17.7)	1.00 (0.44-2.25)	0.9945
	A	154 (63.1)	104 (65.8)	1
	G	90 (36.9)	54 (34.2)	0.89 (0.58-1.35)	0.5803
rs7794745	A/A	35 (29.5)	25 (31.7)	1
	A/T	60 (49.2)	42 (53.2)	0.98 (0.51-1.87)	0.9512
	T/T	27 (21.3)	12 (15.2)	0.62 (0.27-1.46)	0.2751
	A	130 (54.1)	92 (58.2)	1
	T	114 (45.9)	66 (41.8)	0.82 (0.55-1.23)	0.3300
rs251379	A/A	25 (20.5)	20 (25.3)	1
	A/G	61 (50.0)	31 (39.2)	0.64 (0.31-1.32)	0.2230
	G/G	36 (29.5)	28 (35.4)	0.97 (0.45-2.10)	0.9427
	A	111 (45.5)	71 (44.9)	1
	G	133 (54.5)	87 (55.1)	1.02 (0.68-1.53)	0.9131

OR: odds ratio; CI: confidence interval.