Dextromethorphan Dampens Neonatal Astrocyte Activation and Endoplasmic Reticulum Stress Induced by Prenatal Exposure to Buprenorphine

Figure 3

Primary astrocytes derived from the neonates of the buprenorphine group display elevated basal levels of COX-2 and sensitize to the LPS-induced expression of COX-2. Western blot analysis with quantification for COX-2 expression levels in the primary astrocytes at basal (a) or activated (LPS treatment) (b) condition. Data are % of control; vs. Con and vs. Con and ^## vs. Bu.

(a)

(b)