Protective Effect of Melatonin on Nonylphenol-Induced Reproductive and Behavioral Disorders in First-Generation Adult Male Rats

Figure 6

MLT improved histopathological changes induced by NP in the adult testis. Representative photomicrographs of the testis of first-generation adult male rats (H&E stain, ×40) (). Control group (a), MLT20 group (b), NP25 group (c), NP+MLT10 group (d), and NP+MLT20 group (e). (a) Shows normal tissue conditions in the control group; (b) normal tissue conditions and increased spermatozoa population in the MLT20 group; (c) hyperemia (right arrow), edema (down arrow), and vacuolar degeneration (arrow left) in the NP25 group; (d) hyperemia (arrow to the right) and vacuole degeneration (arrow to the left) in the NP+MLT10 group; and (e) normal tissue conditions in the NP+MLT20 group. NP: nonylphenol; MLT: melatonin.