RDW-to-ALB Ratio Is an Independent Predictor for 30-Day All-Cause Mortality in Patients with Acute Ischemic Stroke: A Retrospective Analysis from the MIMIC-IV Database
Table 1
Characteristics of the study patients.
Characteristics
RAR in transform groups (mL/g)
Q1 () 0.8–1.2
Q2 () 1.2–1.5
Q3 () 1.5–2.7
value
General information
Sex, male,
216 (45.9%)
241 (51.4%)
248 (52.5%)
0.090
Age, mean, years
<0.001
Race,
0.176
White
288 (61.1%)
292 (62.3%)
280 (59.3%)
Black
46 (9.8%)
41 (8.7%)
67 (14.2%)
Asian
16 (3.4%)
12 (2.6%)
13 (2.8%)
Other
121 (25.7%)
124 (26.4%)
112 (23.7%)
Alcohol
2 (0.42%)
0 (0.00%)
7 (1.48%)
0.013
Comorbidities,
Hyperlipidemia
271 (57.54%)
241 (51.39%)
196 (41.53%)
<0.001
Atrial fibrillation
139 (29.51%)
191 (40.72%)
206 (43.64%)
<0.001
Myocardial infarction
50 (10.62%)
76 (16.20%)
119 (25.21%)
<0.001
Congestive heart failure
52 (11.04%)
121 (25.80%)
177 (37.50%)
<0.001
Peripheral vascular disease
37 (7.86%)
47 (10.02%)
59 (12.50%)
0.061
Dementia
14 (2.97%)
33 (7.04%)
27 (5.72%)
0.017
Chronic pulmonary disease
49 (10.40%)
81 (17.27%)
96 (20.34%)
<0.001
Rheumatic disease
6 (1.27%)
17 (3.62%)
25 (5.30%)
0.003
Peptic ulcer disease
2 (0.42%)
7 (1.49%)
18 (3.81%)
<0.001
Diabetes
137(14.54%)
173(18.44%)
203(21.50%)
<0.001
Paraplegia
261 (55.41%)
255 (54.37%)
181 (38.35%)
<0.001
Kidney disease
43 (9.13%)
85 (18.12%)
136 (28.81%)
<0.001
Malignant tumor
15 (3.18%)
41 (8.74%)
75 (15.89%)
<0.001
Metastatic cancer
4 (0.85%)
17 (3.62%)
38 (8.05%)
<0.001
AIDS
1 (0.21%)
0 (0.00%)
3 (0.64%)
0.332
Liver disease
6 (1.27%)
12 (2.56%)
54 (11.44%)
<0.001
Hypertension
287 (60.93%)
245 (52.24%)
189 (40.04%)
<0.001
Score system
APSIII
<0.001
SAPSII
<0.001
HAS-BLED score
0.122
Charlson comorbidity index
<0.001
SIRS score
<0.001
SOFA
<0.001
Vital signs
Heart rate (beat/minute)
<0.001
Respiration rate (breath/minute)
<0.001
MBP (mmHg)
<0.001
Temperature (°C)
0.813
SPO2 (%)
0.003
Laboratory results
BUN (mg/dL)
<0.001
Creatinine (mEq/L)
<0.001
WBC (109/L)
0.001
Bicarbonates (mmol/L)
<0.001
Anion gap (mmol/L)
0.062
Chlorine (mmol/L)
0.013
Blood sugar (mg/dL)
0.043
Sodium (mmol/L)
0.259
Potassium (mmol/L)
0.038
PT
<0.001
Platelets
0.055
APTT
0.003
Hematocrit
<0.001
Hemoglobin
<0.001
MCH
<0.001
MCHC
<0.001
MCV
0.315
RBC
<0.001
ALT
<0.001
ALP
<0.001
AST
<0.001
Treatment,
Warfarin
86 (18.26%)
86 (18.34%)
108 (22.88%)
0.125
NOAC
67 (14.23%)
77 (16.42%)
51 (10.81%)
0.042
ANTIPLT
362 (76.86%)
357 (76.12%)
309 (65.47%)
<0.001
PEG/PEJ
19 (4.03%)
25 (5.33%)
29 (6.14%)
0.337
Death situation,
30-day all-cause mortality
60 (12.74%)
82 (17.48%)
142 (30.08%)
<0.001
ICU mortality
42 (8.92%)
49 (10.45%)
84 (17.80%)
<0.001
In-current hospital mortality
59 (12.53%)
83 (17.70%)
141 (29.87%)
<0.001
APSIII: acute physiology score III; SAPSII: simplified acute physiology score II; HAS-BLED: has-bled bleeding risk score; SIRS: system inflammatory response syndrome; SOFA: sequential organ failure assessment; MBP: mean blood pressure; BUN: blood urea nitrogen; WBC: white blood cell; PT: prothrombin time; APTT: activated thrombin time; MCH: average hemoglobin content; MCHC: average hemoglobin concentration; MCV: average red blood cell volume; RBC: total red blood cell; ALT: alanine transaminase; ALP: alkaline phosphatase; AST: aspartate aminotransferase; NOAC: new oral anticoagulant; ANTIPLT: antiplatelet drugs; PEG/PEJ: percutaneous endoscopic gastrostomy/jejunostomy.