Research Article

Graph Theoretical Analysis of Semantic Fluency in Patients with Parkinson’s Disease

Table 1

Demographic and clinical features, and neuropsychological measures of PD patients and healthy controls (means, standard deviations, and group differences).

Features/measuresPD patients
()
Healthy controls
()
Group differences ( values)

Female: Male44 : 4246 : 420.884
Age (years)59.0 (9.5)58.1 (7.0)0.484
Education (years)12.4 (3.2)12.9 (2.4)0.204
Montreal cognitive assessment25.6 (2.4)27.9 (1.4)<0.001
Levodopa equivalent daily dose (mg)243.3 (248.6)
Motor symptoms
Hoehn and Yahr scale1.4 (0.5)
MDS-UPDRS III: Motor examination21.8 (12.6)
Disease duration (years)1.6 (2.2)
Duration of motor symptoms (years)2.8 (2.4)
Other non-motor functions
MDS-UPDRS I: Non-motor experiences of daily living5.3 (4.0)
Beck depression inventory-II2.7 (2.0)2.1 (1.7)0.039
REM sleep behavior disorder screening questionnaire3.7 (2.0)1.9 (1.8)<0.001
Epworth sleep scale3.1 (3.2)3.2 (2.3)0.820

Note: MDS-UPDRS, the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale; group differences, values of two-sample t-tests, or Chi-square test as appropriate; asterisks (), a significant difference (two-tailed, Bonferroni correction for seven tests).