The Effects of Poria cocos on Rho Signaling-Induced Regulation of Mobility and F-Actin Aggregation in MK-801-Treated B35 and C6 Cells

Figure 1

PRP and WP differentially regulate MK-801-induced RhoGDI1, RhoA, and CDC42 regulation. Western blotting revealed the expression changes of RhoGDI1, RhoA, and CDC42 induced by PRP/WP in (a) B35 and (c) C6 cells treated with MK-801. The protein expression was quantified by using ImageJ software. Beta-actin was used as a normalization control to calculate the relative expression of the examined targets. The bar chart was constructed according to the data of three independent western blot experiments that analyzed three different batches of protein extracts of drug-treated (b) B35 and (d) C6 cells. The data was analyzed by using Student’s -test ( value<0.05; value<0.01) analysis.

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