Evaluation of the Possible Mechanisms of Antihypertensive Activity of Loranthus micranthus: An African Mistletoe

Table 1

Changes in serum lipid levels in mice orally administered with the various fractions recovered from Loranthus micranthus methanolic leaf extract for 21 days.

			Treatment group
		Control	NBF-LMME	WF-LMME	CF-LMME	EAF-LMME
Parameter	Day 0	Day 21	Day 21	Day 21	Day 21	Day 21
T-CHOL, mg/dL	88.9±0.8^a	114.3±3.5^b	91.9±0.4^a	95.5±2.8^c	107.1±0.7^b	108.9±2.8^b
% Δ	—	(28.6)	(3.4)	(7.4)	(20.5)	(22.5)
LDL-CHOL, mg/dL	18.2±0.3^a	42.2±4.3^b	23.7±0.9^c	25.0±3.4^c	35.3±0.6^d	36.1±3.1^d
% Δ	—	(131.9)	(30.2)	(37.4)	(94.0)	(98.4)
TAG, mg/dL	147.3±2.5^a	152.8±0.6^b	138.5±3.4^c	148.1±4.0^a	151.9±1.2^b	152.2±2.7^b
% Δ	—	(3.7)	(−6.0)	(0.5)	(3.1)	(3.3)
HDL-CHOL, mg/dL	41.3±0.9^a	41.6±0.7^a	41.0±0.4^a	40.8±0.7^a	41.5±0.5^a	40.6±0.2^a
% Δ	—	(0.7)	(−0.7)	(−1.2)	(0.5)	(−1.7)

Data are mean ±SEM of triplicate assays. Figures in each row with different superscript letters (a, b, c, d) are significantly different (𝑃<0.05). Figures in parentheses represent percentage change (%Δ) in day 21 lipid level compared to day 0 (increase = +; decrease = −). This reflects the multiple range test statistics used to compare the mean values of variables measured across the Loranthus micrathus fraction groups.