AP-1 as a Regulator of MMP-13 in the Stromal Cell of Giant Cell Tumor of Bone
Figure 2
Expression of AP-1 proteins in the nucleus of GCT stromal cells. The AP-1 screening assay examines the protein level of FosB, c-Fos, Fra-1, Fra-2, JunB, JunD, and c-Jun of the AP-1 family in the nuclear extracts of IL-1β stimulated stromal cells. The specific competitor was used to determine specific binding. Values represent the means ± SEM of triplicate experiments after being normalized to the background control. is versus corresponding conditions with specific competitor. Statistical comparison by analysis of variance with post hoc Tukey’s tests.
