Review Article

Transcriptional Modulation of Heat-Shock Protein Gene Expression

Figure 1

Signal transduction pathways activated by STAT1, STAT3, NF-IL6, p53, and the heat-shock response (HSR) via HSF1 binding to the heat-shock response element (HSE) and integrating to modulate Hsp transcription, which is known to be dysregulation in different pathological diseases.
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