Mechanism(s) of Toxic Action of Zn²⁺ and Selenite: A Study on AS-30D Hepatoma Cells and Isolated Mitochondria

Figure 8

Simultaneous recordings of four mitochondrial parameters (respiration, ΔΨ_mito, K⁺, and Ca²⁺ fluxes) with the help of O₂, TPP⁺, K⁺, and Ca²⁺-selective electrodes after treatment of isolated RLM with Cd²⁺ in the absence (a) or presence of CsA (b). The additions of Cd²⁺ (5 μM) are indicated by arrows. The remainder is as in Figure 5.

(a)

(b)