Hsp70 and Its Molecular Role in Nervous System Diseases

Table 2

Hsc70 and neurodegenerative diseases.

Disease	Neurons affected	Hsc70 levels	Frequency
Alzheimer disease	entorhinal cortex and hippocampus	Low	High
Parkinson disease	dopaminergic neurones in the substantia nigra pars compacta	Intermediate	Intermediate
Amyotrophic lateral sclerosis	motor neurons of the spinal cord and motor cortex	High	Low