Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement

<table>Increased MMP-28 secretion is accompanied with cell migration. The data show that furin enhances cell migration in MMP-28 transfected COS-1 cells. This enhancement is accompanied by elevated MMP-28 trafficking in the secretory pathway. COS-1 cells transfected with cDNAs as indicated were examined by transwell migration assay. Each sample was examined as triplicates and repeated three times. Each bar represents the mean <svg height="9.5625" id="M40" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). </table>

Biochemistry Research International

fig6

Figure 6

Figure 6: Furin Functions as a Nonproteolytic Chaperone for Matrix Metalloproteinase-28: MMP-28 Propeptide Sequence Requirement 