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Biochemistry Research International
Volume 2012 (2012), Article ID 248135, 12 pages
http://dx.doi.org/10.1155/2012/248135
Review Article

Sphingolipid and Ceramide Homeostasis: Potential Therapeutic Targets

1School of Biology and Chemistry, Biomedical Sciences Research Complex, University of St Andrews, North Haugh, KY16 9ST, UK
2Biophysical Sciences Institute, School of Biological and Biomedical Sciences and Department of Chemistry, University of Durham University Science Laboratories, South Road, Durham DH1 3LE, UK
3School of Medicine and Health, Durham University, Queen's Campus, Stockton-on-Tees TS17 6BH, UK

Received 31 July 2011; Accepted 20 October 2011

Academic Editor: Todd B. Reynolds

Copyright © 2012 Simon A. Young et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Amanda M. Goldston, Rhonda R. Powell, and Lesly A. Temesvari, “Sink or swim: Lipid rafts in parasite pathogenesis,” Trends in Parasitology, vol. 28, no. 10, pp. 417–426, 2012. View at Publisher · View at Google Scholar
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  • Maja Jazvinšćak Jembrek, Patrick R. Hof, and Goran Šimić, “ Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and A β Accumulation ,” Oxidative Medicine and Cellular Longevity, vol. 2015, pp. 1–17, 2015. View at Publisher · View at Google Scholar
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  • Erica V. De Castro Levatti, Marcos S. Toledo, Renata Watanabe Costa, Diana Bahia, Renato A. Mortara, Helio K. Takahashi, and Anita H. Straus, “Leishmania (Viannia) braziliensis Inositol Phosphorylceramide: Distinctive Sphingoid Base Composition,” Frontiers in Microbiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Justyna Brodowicz, Edmund Przegaliński, Christian P. Müller, and Malgorzata Filip, “Ceramide and Its Related Neurochemical Networks as Targets for Some Brain Disorder Therapies,” Neurotoxicity Research, 2017. View at Publisher · View at Google Scholar
  • John G. Mina, Julie K. Thye, Amjed Q. I. Alqaisi, Louise E. Bird, Robert H. Dods, Morten K. Grøftehauge, Jackie A. Mosely, Steven Pratt, Hosam Shams-Eldin, Ralph T. Schwarz, Ehmke Pohl, and Paul W. Denny, “Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites,” Journal of Biological Chemistry, vol. 292, no. 29, pp. 12208–12219, 2017. View at Publisher · View at Google Scholar