Research Article

Effect of Vitamins A, C, and E Supplementation in the Treatment of Metabolic Syndrome in Albino Rats

Table 1

Effect of vitamins A, C, and E on glucose, insulin, and insulin resistance.

Group Glucose (mmol/L)Insulin (μU/mL)HOMA-IR

I4.28 ± 0.312.98 ± 1.420.56 ± 0.23
II6.50 ± 0.83c17.01 ± 4.04c4.81 ± 0.68c
III5.28 ± 0.84b,d4.53 ± 2.38a1.06 ± 0.43a
IV4.89 ± 0.42a3.96 ± 1.48a0.84 ± 0.26a
V4.75 ± 0.30a5.09 ± 1.07a1.07 ± 0.19a
VI4.83 ± 0.43a5.40 ± 1.33a1.14 ± 0.22a

HOMA-IR: homeostasis model assessment-insulin resistance, I: normotensive control, II: hypertensive control, III: group treated with vit C, IV: group treated with vit A, V: group treated with vit E, and VI: group treated with all the vitamins. Values are expressed as mean ± SD; . aP < 0.01 when compared with group II, bP < 0.05 when compared with group II, cP < 0.01 when compared with group I, and dP < 0.05 when compared with group I by Dunnette’s multiple comparison test.